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Description
Hyperhomocysteine genetic polymorphism of methylenetetrahydrofolate reductase in young adults with ischemic stroke

The TRPV4 antagonist GSK2193874, as a preventive treatment, inhibits NMDAR-mediated excitotoxicity and NLRP3 inflammasome activation, and reduces the seizure rate [194]

Tai ST, Fu YH, Yang YC, Wang JJ

Summary Overall, the de novo NAD + synthetic pathway is compromised in experimental models and human cells of AKI, while NAD + replenishment attenuates AKI

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