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In a previous study, mesenchymal stem cell (MSC)-derived exosomes effectively restored the activity of genes linked to the adaptability of synapses and decreased the expression of A in individuals with AD

Furthermore, in a recent study from the United Kingdom, the calculated frequency of individuals predicted to carry two mutant pathogenic ATP7B alleles was ~1 per 7,000 individuals, with heterozygote mutations found in up to 2.5% of the general population 12

That said, there is significant overlap with the broader optimization population

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