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TZDs activate PPAR to promote adipogenesis and fatty acid uptake, increase glucose utilization and decrease glucose production, and subsequently enhance insulin sensitivity by upregulating genes involved in lipid metabolism, such as CD36, FABP4 , and LPL (395)

In Mastery of Surgery, 5th ed

Recent studies have reported that lipids from neighboring adipose tissues, lipoproteins, lysophospholipids, and intracellular storage fat have the potential to maintain viability and growth of cancer cells 6,7,8,9

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