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Dark spots can often be caused by sun exposure, hormonal changes, inflammation, or injury to the skin
Rights and permissions About this article Cite this article Morris, G., Anderson, G., Dean, O
In the presence of oxidative stress or specific electrophilic stimuli , critical cysteine residues on KEAP1 undergo modifications that disrupt KEAP1-mediated repression, resulting in the stabilization and release of Nrf2
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Reported observations include: Improved mobility Better recovery timelines Reduced dependency on long-term pain management strategies Conventional veterinary practice may remain cautious due to limited formal clinical data
