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186,187,188,189 In addition, the transcription factor Twist1 upregulates the expression of downstream target genes of TCF4, such as HGF, VEGF, and IGF-1, by forming complexes with TCF4 and -catenin, promoting the proliferation of dermal papilla cells and inducing hair follicle regeneration

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23 In December 1987, Stephen Blooms team confirmed in a Lancet paper that GLP-1(7-36) is a human intestinal hormone that stimulates insulin production in the pancreas and lowers blood sugar
& Stenn, K

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