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J Clin Endocrinol Metabol 99(8):29953004 Magalhes-Padilha D, Duarte A, Arajo V, Saraiva M, Almeida A, Rodrigues G et al (2012) Steady-state level of insulin-like growth factor-I (IGF-I) receptor mRNA and the effect of IGF-I on the in vitro culture of caprine preantral follicles

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Perhaps these proteins predispose to polar mycelial growth rather than isotropic spherule growth