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Furthermore, Wnt ligands during mid-to-late anagen are largely expressed in the matrix and not in the DP 40,41,42 , suggesting that the matrix is the predominant source of Wnt ligands that activate the pathway in both the DP and the matrix

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reported that the five most common symptoms of hospitalized patients were fatigue (28.4%), pain/discomfort (27.9%), sleep difficulties (23.5%), breathlessness (22.6%), and limited regular activity (22.3%)

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