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A total of 165 ALDH7A1 pathogenic variants have been reported in the literature, but no clear genotype-phenotype correlation has been established

But that doesnt mean its impossible that the two are linked

Cryotherapy has demonstrated particular promise for rheumatoid arthritis patients

This is often due to the accumulation of Ama, which interferes with normal physiological processes and blocks proper nourishment at the tissue level

Keywords: cutaneous manifestation of vitamin b12 deficiency, adisonian mimick, vitamin b12 deficiency symptoms, cutaneous hyperpigmentation, hyperpigmentation Introduction The deficiency of vitamin B12 can cause specific skin manifestations, such as hyperpigmentation, vitiligo, angular stomatitis, and hair and nail changes [1]