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These enzymes form a multienzyme metabolic complex, which translocates to the nucleus during S (DNA replication) and G2/M (DNA damage checkpoint) phases, and is required for biosynthesis of the nucleotide precursor, thymidylate, which is critical to DNA synthesis and repair

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The application of metabolomics in investigating anti-diabetic activity of medicinal plants

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If their response is (1), you could let them know that some degenerative brain diseases appear to be caused by increased ferroptosis, as I described in a recent article: Ferroptosis of Microglia Drives Neurodegeneration This alone may be interesting enough to stimulate a great conversation
