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Finally, a double-blind RCT comprising 64 patients diagnosed with CTS requiring surgical decompression of the median nerve compared oral ALA 600 mg/d to placebo following surgery for CTS

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Alternatively, endocytosis and/or transcytosis of GSH transporter-targeted ligands may be assayed by in vivo bioimaging techniques using for instance near-infrared dyes or radioactive labels conjugated thereto, resulting in at least 10, 20, or 50% enhanced retention in CNS area of the ligand at given time-points (based on region of interest (ROI) pixel quantification), as compared to appropriate control conditions (e.g., comparison to reference compounds lacking GSH moieties)

Although the healing process is possible, inhaled exposure can also cause pulmonary problems such as pneumothorax, interstitial emphysema, pneumatocele, interstitial fibrosis, and pneumomediastinum