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The GCH1/BH4/DHFR axis functions independently of GPX4 and contributes to antioxidant defense through the synthesis of BH4

Montagut C, Argils G, Ciardiello F, Poulsen TT, Dienstmann R, Kragh M, Kopetz S , Lindsted T, Ding C, Vidal J, Clausell-Tormos J, Siravegna G, Snchez-Martn FJ, Koefoed K, Pedersen MW, Grandal MM, Dvorkin M, Wyrwicz L, Rovira A, Cubillo A, Salazar R, Desseigne F, Nadal C, Albanell J, Zagonel V, Siena S, Fumi G, Rospo G, Nadler P, Horak ID, Bardelli A, Tabernero J