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An alternative paradigm proposes a stochastic model where all dividing keratinocytes are functionally equivalent and generate dividing and differentiating daughters with equal probability [4, 5]

[DOI] [PubMed] [Google Scholar] Kraus T., Uttamsingh V., Anders M.W., Wolf S

It is defined by the interaction of free intracellular iron or iron-containing enzymes with oxygen and polyunsaturated fatty acids (PUFAs), resulting in high levels of membrane lipid peroxides [99]

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Posadas et al