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Treatment with methylcobalamin or hydroxocobalamin may unmask this condition

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B12 is much more complicated, it requires specialized transportation as well as multiple conversion steps

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In the case of suspected cobalt hypersensitivity, an intradermal test dose should be administered because anaphylactic shock and death have followed parenteral administration of methylcobalamin

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However, no research directly compares continuous use versus cycling protocols (such as 12 weeks on, 4-8 weeks off), leaving optimal long-term strategies somewhat uncertain

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But methylcobalamin is NOT illegal in USA

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