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Potapova, I

Blood-brain-barrier-penetrant AngIV analog Studied as a metabolically stabilized, orally active angiotensin-IV derivative designed to reach the brain in animal pharmacokinetic work

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Lipid radicals bind with oxygen (O 2 ) to produce a lipid peroxyl radical (LOO), which yields hydrogen from adjacent PUFA to form lipid hydroperoxides (LOOH) and a lipid radical and simultaneously initiate a new lipid radical chain reaction ( Lipoxygenases (LOXs) are considered one of the central players in ferroptosis (Shah et al., 2018)

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