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The trials demonstrated that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo

I only had a sore arm after the first dose

PubMed PMID: 502936

When circulation is compromised, oxygenation is low, or collagen is depleted, the result is visible: dilated blood vessels, pooled blood, and increased pigmentation all show up more easily here than anywhere else on the face

This was demonstrated by the fact that administration of the peptide counteracted 5-HT receptor-dependent symptoms induced by pargyline + L-tryptophan, i.e., hyperthermia and wet dog shake related to 5-HT2A agonism, but not 5-HT1A-related forepaw treading, hind limb abduction, or hypothermia