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Zearalenone and alpha-zearalenol inhibit the synthesis and secretion of pig follicle stimulating hormone via the non-classical estrogen membrane receptor GPR30

They reported that dosage to be nearly equivalent to the manufacturers recommended human dose of 675 mg per day for a 60 kg adult, or 422 mg/m 2 [43]

Although the exact mechanism is unknown, this rise in melanocyte activity has been shown to be stimulated by prostanoids, cytokines, chemokines, and other inflammatory mediators as well as reactive oxygen species that are released during the inflammatory process

In addition, major organs (heart, liver, spleen, lungs, kidneys) were isolated from the sacrificed mice at 24 h post-injection

(2015) study