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For adults under age 65, the easiest way to get B12 is to take at least one 2,000 mcg supplement each week or a daily dose of 50 mcg

Refrigeration is recommended

There is agreement that the malabsorption of vitamin B12 can be suspected in people with autoimmune disorders, in patients who have had gastric surgery, in people with a family history of pernicious anemia or with positive test results for serum antibodies against intrinsic factor or parietal cells

It depends on your individual needs

The usual daily recommended amounts of cyanocobalamin, vitamin B12 either through dietary intake or supplementation should be taken during pregnancy (see Dosage)