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Consistent supplementation, proper hydration, and correct timing all play essential roles in achieving these benefits effectively

Studies show that elevated TMAO decreases mTOR and p70S6K expression, causes hippocampal neuron loss and synaptic ultrastructural damage, and worsens cognitive function in mice, with higher TMAO leading to more severe deficits (Li et al., 2018)

However, if inflammation remains elevated chronically, it can result in a sustained state of excess inflammation and oxidative stress

doi: 10.1007/s13679-017-0261-z 37

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