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l-carnitine administration significantly improved cognitive and renal functions.. Parnetti, L, et al, Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type. in European Journal of Clinical Pharmacology , Volume 42, Issue 1, 1992, pp 89 - 93

MAPKs are the serine/threonine protein kinases that activate the cellular stress caused by heat shock and mitogen osmotic stress, as well as inflammatory cytokines (such as TNF-, IL-1, and IL-6) [60]