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The mechanisms that may contribute to the induction of oxidative damage in diabetic patients include hyperglycemia-induced glucose auto-oxidation, non-enzymatic glycation of proteins and lipids, increased sorbitol pathway activity, oxidation of AGEs, and formation of prostaglandin H2 (PGH2) [311]

Because it is a substance naturally produced by the body, it is generally well-tolerated for daily use

Furthermore, the discovery that HLA-G-bearing exosomes (HLA-Gev) are potent mediators of systemic immune suppression has spurred interest in exosome-targeted therapies

Think of it like pouring beer into a glass

Rendeiro AF, Casano J, Vorkas CK, Singh H, Morales A, DeSimone RA, et al