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One of the most widely used peptides in physician-supervised clinical practice before the 2023 restriction

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Meantime, DDCu was reduced to Cu + by cellular glutathione to react with lipoylated proteins of the tricarboxylic acid cycle and destabilize the FeS cluster proteins, leading to the aggregation of dihydrolipoamide S-acetyltransferase and cuproptosis in cancer cells

Although these findings appear promising, the utility of intravenous NAC repletion as a therapeutic strategy in PD is greatly limited by invasiveness and inconvenience of intravenous delivery