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Additionally, astaxanthins ability to upregulate brain-derived neurotrophic factors and activate the extracellular-signal-regulated kinase (ERK) pathway may further support synaptic plasticity and cognitive function [37]

Clin Schizophr Relat Psychoses 7:113 Xiao C, Giacca A, Lewis GF (2011) Short-term oral -lipoic acid does not prevent lipid-induced dysregulation of glucose homeostasis in obese and overweight nondiabetic men

(2004) L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo : studies upon the profile of polyunsaturated fatty acids

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Similarly, ropivacaine, a commonly used local anesthetic, has been found to suppress the growth and stemness of ovarian cancer cells while promoting ferroptosis via the PI3K/AKT signaling pathway (120)