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Most roseoflavin-resistant strains studied until now carry mutations in the regulatory region upstream of the rib operon (more specifically, in the aptamer of the riboswitch), disrupting the negative feedback mechanism, resulting in significantly higher expression 184,185

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Haematococcus algae can be categorized into two cell stages (described in Section 2.3.3), and these stages can be cultured simultaneously in a single-stage continuous or batch system
