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This combination promotes stem cell activation and their progression into actively cycling follicles
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132,133 However, HSD17B13 knock-out mice also show increased hepatic steatosis and inflammation phenotype, mainly due to an increase in de novo lipogenesis
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In contrast, elevated ROS levels drive IDO1 translocation into the cytosol, where it binds mitochondria-released heme to form an active holoenzyme
