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Nitrous oxide-mediated vitamin B12 deficiency may lead to an acute prothrombotic state by elevating homocysteine levels (23)

but with much larger oral doses, vitamin B12 appears in plasma much sooner as a result of passive diffusion, independent of the presence or absence of intrinsic factor

Only a handful of people Sinha pointed to a recent study published in the online journal of JAMA which found an association between high intakes of vitamins B6 and B12 and hip fractures in older women

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