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These two directions not only rest on solid clinical infrastructure but also hold strong potential to rapidly advance AML therapy from conventional regimens toward a biomarker-driven precision paradigm
Moreover, CRISPR/Cas9 can be destroyed by the cellular immune response, thus reducing its therapeutic effect (Miah et al., 2019)
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doi: 10.1182/blood-2003-03-0672 39 NiSYuanYKuangYLiX
The absorbance was measured at 750 nm against the reagent used as a blank
