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Description
Nonsense-mediated mRNA decay inhibition synergizes with MDM2 inhibition to suppress TP53 wild-type cancer cells in p53 isoform-dependent manner

Abstract Cancer has become a major public health issue that seriously threatens human health

Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38(+) macrophages and NAD(+) decline

Pea-Bautista C, Vento M, Baquero M, Chafer-Pericas C

Biochim Biophys Acta 2010;1797(6-7): 698-709