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There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, or concomitant use of other drugs

38 Other hypotheses for the mechanisms behind headaches in PACS include the ability of the virus to bind to angiotensin-converting enzyme 2 (ACE2) receptors in neurons and glia of CNS structures such as olfactory groove, olfactory bulb, and trigeminal ganglia

It also has antiparasitic activity, but is thought to benefit rosacea patients by reducing inflammation and constricting superficial blood vessels

10.1016/j.jhep.2013.08.011 J
[Google Scholar] 39.Thompson HS and Staines NA, Gastric administration of type II collagen delays the onset and severity of collagen-induced arthritis in rats