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Negatively charged nanoparticles, on the other hand, have better stability and lower immunogenicity (Wang et al., 2025c)

Because disorders of the GI tract can interfere with the absorption of B12, the level of this vitamin in the blood is sometimes used as a test of gut health

Liu KY, Mistry RJ, Aguirre CA, Fasouli ES, Thomas MG, Klamt F, Ramsden DB, Parsons RB (2015a) Nicotinamide N -methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3

Experimental evidence from knockout models suggests that reduced NNMT activity is associated with resistance to tumor formation, leading to speculation about a possible role for this enzyme in cancer biology