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Poster Session II - RECOVERY, REHABILITATION AND OUTCOME 03.00 - RECOVERY, REHABILITATION AND OUTCOME - 03.03 - PROGNOSIS AND OUTCOME AFTER STROKE P844 - ESOC25-573 RETINAL MICROVASCULAR BIOMARKERS FOR DYNAMIC EVOLUTION OF CEREBRAL INFARCT VOLUME Dmytro Pavlenko 1,2 , Francesca Chappell 3,4 , Stewart Wiseman 2,3,5 , Charlene Hamid 2,5 , Una Clancy 2,3 , Carmen Arteaga Reyes 2,3 , Dmytro Zhaboiedov 1 , Fergus Doubal 2,3 , Tom MacGillivray 2 , Joanna Wardlaw 2,3,5 1 Department of Ophthalmology, Bogomolets National Medical University, Kyiv, Ukraine, 2 Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom, 3 UK Dementia Research Institute at the University of Edinburgh, Edinburgh, United Kingdom, 4 Row Fogo Centre, University of Edinburgh, Edinburgh, United Kingdom, 5 Edinburgh Imaging Facilities, Edinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom Background and Aims: Ischaemic stroke may affect retinal vascularity over time and might reflect stroke subtype

294296 In mice orally administered metformin, the metformin delayed the onset of fructose-induced liver stenosis through reduced fructose function, in which alterations of MMPs and TIMP-1 concentrations in the intestine occurred