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and nGPX4 has a canonical nuclear localization signal, but more importantly lysine/arginine rich domains (similar to that in protamines) which facilitates nGPX4 binding to sperm DNA enabling oxidation of cysteines in protamines [47]

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Genes Genom

10.1016/j.abb.2016.08.003 Arch
[69] Agyeman AS, Chaerkady R, Shaw PG, et al