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Popichak KA, Hammond SL, Moreno JA et al (2018) Compensatory expression of Nur77 and Nurr1 regulates NF-B-dependent inflammatory signaling in astrocytes

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Activation of the NRF2/SLC7A11/GPX4 signaling pathway leads to elevated GSH levels, reduced MDA and ROS accumulation, suppression of neuronal ferroptosis, lipid peroxidation, and amino acid antioxidant dysfunction, ultimately mitigating neuronal injury

Nature 492 , 108112 (2012)
