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POMC-derived peptides, particularly -MSH, stimulate MC1R of melanocytes, releasing the intracellular second messenger cAMP, which in turn induces a cascade of intracellular molecular events, ultimately activating the microphthalmia-associated transcription factor (MITF)

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Graham MR, Baker JS , Evans P, Kicman A, Cowan D, Hullin D, Thomas N, Davies B

Sep-Oct 2016;61(5):469-81
