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Description
Cognitive and functional effects may continue to develop after the treatment period ends, as neuroplastic changes consolidate over time
Limitations of the Evidence The honesty matters
Metabolic panel : Comprehensive metabolic panel every 36 months to assess renal function, electrolytes, and liver enzymes
Some users report a small reduction in minor joint discomfort or improved sleep quality
In a phase II randomized trial in patients with treatment-naive metastatic GEA, the addition of ziv-aflibercept to mFOLFOX6 did not demonstrate an advantage in terms of 6-month PFS (primary endpoint), RR and OS (58, 59)
