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Thats the promise of Smart Brothers Dihexa, a peptide (also called PNB-0408) that crosses the blood-brain barrier, binds hepatocyte-growth-factor (HGF) with femtomolar affinity, and turbo-charges HGF/TrkB signallingseven orders of magnitude more potent than BDNF itself

12a,b) and His tag in the rLOX-PP (with His tag) treated cells (Fig

Reconstitution does not alter the in vivo dihexa half life (which is determined by metabolism and clearance), but it significantly affects ex vivo peptide stability before administration

Cell cycle regulation IPA analysis of our proteomics data detected alterations in cell cycle regulation after treatment with MGT (Fig

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