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Description
Although IDH1/2 mutants exclusively produce D-(R)-enantiomer of 2-HG, the L-(S)-enantiomer 2-HG accumulation is induced in response to hypoxia and prevent TET activity

This page summarizes laboratory and animal research and links to primary literature
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An initial hypothesis proposed that AOD 9604 may bind and activate -3-adrenergic receptors, which are present on the surface of white adipose tissues
