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Similarly, PIPLC releases PrP C but not PrP Sc from the cell surface after 5 hours [Taraboulos 1990], but it does eventually cure cells of PrP Sc infection (presumably by depletion of PrP C substrate) after 3 days [Enari 2001]

Proc Natl Acad Sci U S A 97: 56215626, 2000
Pediatric Spinal Cord Injury

(2) excessive production of matrix metalloproteinases (MMPs), which collectively exacerbate inflammation and contribute to cartilage degradation [11]
