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Notably, treatment with different formulations led to a significant increase in the expression levels of p-STING, TBK1, cGAS, and IRF3 proteins in mouse tissue samples (Fig

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Using genetically modified Drosophila , Hartwig et al

There is a lack of substantial data that enables researchers to conclude if depth of ablation is sufficient, but the current data suggests that its around 1mm to 2mm in depth

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