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The 12 mg group achieved 24.2% weight loss at 48 weeks in Phase 2, and 28.7% at 68 weeks in the Phase 3 TRIUMPH-4 trial

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Combination Side Effects Since some of the side effects of these medications overlap, combining them may lead to more severe side effects in some individuals, such as dizziness, drowsiness, and gastrointestinal side effects like constipation, gas, bloating, and nausea

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