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doi: 10.1016/S0165-0173(99)00014-4

J Endocrinol (2004) 180(2):24755.10.1677/joe.0.1800247 224 WuSYangWDe LucaF

(4) The researchers investigated cell culture models of fibrosis, which also expressed senescence markers such as more -galpositive cells and higher p16 and p21

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These findings outline a molecular framework, which link mood dysregulation, addictive behaviors and highlight how depression and drug exposure lead to enduring changes in gene regulation and neural function
