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In hepatocarcinogenesis, aflatoxin B1 (AFB1) exposure primarily induces oxidative stress through CYP3A4-mediated metabolic activation, generating ROS and MDA that directly cause DNA damage [389, 390]

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The neurodevelopmental sequelae of psychiatric disorders involve intersecting genetic [12, 13] and environmental factors [14]

At the same time, we also performed single-gene GSEA analysis of GPX3 in the GSE148420 dataset (dataset of gene expression differences before and after renal ischemia-reperfusion)

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