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Phase 3 trial investigating nausea management in GLP-1 agonist users

Despite recent advances in the cancer therapy that significantly extend patient survival, many individuals still undergo drug resistance, even to multiple chemotherapeutic drugs, known as multidrug resistance (MDR)

The former mechanism is preferred because RS scavengers can be consumed during the reaction and may generate toxic radicals derived from the chelators (Halliwell and Gutteridge, 2015)

5-Amino-1MQ is short for 5-amino-1-methylquinolinium

Dalzoppo D, Di Paolo V, Calderan L et al (2017) Thiol-activated anticancer agents: the state of the art