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The results showed that more patients in the combination group achieved the primary outcome and resolution of MASH than did those in the placebo group, while there was no significant difference between the vitamin and placebo groups, suggesting the beneficial effect of pioglitazone on MASH
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Kidney Int (2004) 65(6):217283

Gandhi L, Johnson BE

the simultaneous presence of mitochondrial abnormalities in cardiac and neural tissues of comorbid patients, suggesting a potential shared cellular defect