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[63] The specific effects of various noble kavas depend on various factors, such as the cultivar used (and the related specific composition of kavalactones), age of the plant, and method of consumption

While intuitively appealing, this theory is not supported by physiological evidence

Not approved for use in humans or animals

[102] Surgery [edit] If medical treatment is not effective, surgery may be performed

It is worth noting that we further stratified diabetes based on obesity status since obesity is a common and metabolically significant comorbidity in diabetes, and its presence may influence both PA levels and their associations with different disease status