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Intracellular GSH depletion is regarded as an early step of apoptosis as it occurs before loss of mitochondrial integrity, cytochrome c release, and activation of caspases [8]
February 2001 3

This research was funded by Instituto de Salud Carlos III (PI23/00815) (co-funded by European Regional Development Fund A way to make Europe)

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Detrimental Effects of Sickness Behavior on Metabolic Disease Due to the close interaction between the immune system and tissues involved in regulating systemic metabolism, it is not surprising that infection also negatively impacts metabolic disease