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Cynader, Pyruvate Released by Astrocytes Protects Neurons from Copper-Catalyzed Cysteine Neurotoxicity

Treatment of the BV2 cell line with -synuclein increases the secretion of exovesicles expressing the MHC Class II and TNF- molecules on the surface as well as inducing neuronal apoptosis (Chang et al., 2013)

The potential for a placebo effect and the confounding influence of weight loss on PD symptoms also require careful consideration in interpreting results

Injected peptides reach systemic circulation fast and are employed when a direct, dependable effect is required

At the molecular level, their phenolic hydroxyl groups readily donate hydrogen atoms to neutralize reactive oxygen and nitrogen species, forming relatively stable phenoxyl radicals through resonance delocalization across aromatic rings (9497)