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Description
The methylated cGAS can binds with UHRF1 to promote cGAS chromatin sequestration and loss its activity, and eventually suppress the IFN-I responses (124)
Remarkably, nuclear localization of the 2-oxo acid dehydrogenase complexes has recently been discovered, in addition to their traditional mitochondrial localization (4447)
Calculations suggest that, compared with monomers dissolved in water, vesicular solubilization increases the concentration of long-chain fatty acids near the enterocytes brush border membrane by a factor of 100,000 and micellar solubilization by a factor of 1,000,000
The RMSD of protein/ligand was obtained within 4.8
What prompted Kobe to go low
