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Researchers tracking tirzepatide weight loss timelines often reference these same comorbidity thresholds because they align with the clinical trial inclusion criteria

The demyelination observed in this study in the cuprizone pellet group is in the early phase at 3 weeks, and a longer period of exposure to cuprizone of 5 weeks may have resulted in a more severe demyelinating effect 39

Ann Bot 116:487496 de Pinto MC, Locato V, Paradiso A, De Gara L (2015b) Role of redox homeostasis in thermo-tolerance under a climate change scenario

Acknowledgements We are grateful to Prof

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