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1 Introduction Sjgrens syndrome (SS) or Sjgrens disease (SjD) is an autoimmune disease that primarily causes dryness of the exocrine glands, in which the salivary and lacrimal glands are predominantly affected

The follow-up that matters for this specific compound landed in 2018, when a small-molecule NNMT inhibitor was given to obese mice

Li DW, Spector A (1997) Hydrogen peroxide-induced expression of the proto-oncogenes, c-jun , c-fos and c-myc in rabbit lens epithelial cells

Lipid-raft-mediated direct cytosolic delivery of polymer-coated soft nanoparticles

The mechanisms of tissue damage in this disease are not fully understood, although it is believed that increased intracellular cystine leads to alteration of GSH levels (Levtchenko et al., 2005)