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During the pre-stroke phase, sudden brain hypoxia damages the BBB, causing neuroinflammation, cytotoxic edema, production of reactive oxygen species, breakdown of tight junctions and the extracellular matrix, and increased BBB permeability

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Oral glutathione is generally considered less invasive than intravenous (IV) glutathione administration

The toxicity of the mycotoxin is based on a balance between the rate of primary activation of AFB 1 and the rate of detoxification of primary metabolites or repair of cellular damage, determined by the relative activity of enzymes responsible for these reactions